학회소개 
| 한국분자·세포생물학회 학술상 생명과학상 수상자 | |
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조진원 (연세대학교 생명시스템대학 시스템생물학과) Jin Won Cho is a professor at both the Department of Integrated OMICS for Biomedical Science (WCU Program) and Department of Systems Biology at Yonsei University. He received his B.S. and M.S.(Advisor: Professor Young Min Kim) degrees from Yonsei University and earned his Ph.D. degree in glycobiology from the University of California, Davis in 1993. During his graduate studies under the supervision of Professor Frederic Troy, he developed a method to produce unique glycosphingolipids in which their sialyl residues are polysialylated using E. coli K1 polysialyltransferase. After completing his postdoctoral research at SUNY Stony Brook (Advisor: Professor William Lennarz), he joined the faculty of Yonsei University in 1996 and has served as a professor ever since. Until 2000, he continuously studied the functional roles of polysialic acids in sea urchin development. However, he suddenly changed his research field from polysialic acid to O-GlcNAc modification, a research field not well known at the time. His first report in this new research field was presented in 2006. The research was on the elucidation of functional role of O-GlcNAc modification on p53 and identification of its modification site, which was mysterious for the last 10 years. Then, his group elucidated the functional roles of O-GlcNAcylation and its modification sites on NF-κB p65 which kept activating in patients with diabetes complications. His group also found that in various cancer cells, glucose from glycogen degradation under a glucose deprivation condition was used to make UDP-GlcNAc through a hexosamine biosynthetic pathway instead of producing ATP to modify more O-GlcNAc on various proteins. This finding led Dr. Cho to study more of the relationship between O-GlcNAc modification and metastasis of cancer cells. Finally, his group found O-GlcNAc modification occurring on Snail1, a repressor of E-cadherin expression and its role in epithelial mesenchymal transition. He served as the secretary of the Molecular Biology News Committee, treasurer, general secretary, and chair of the Academic Research Awards Committee and currently serves as chair of the Education Committee of KSMCB. He is now the national representative of the International Glycoconjugates Organization and is the organizer of the 24th International Symposium on Glycoconjugates in 2017.A Representative papers |
| 한국분자·세포생물학회 학술상 Molecules and Cells (M&C) 우수논문상 수상자 | |
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최동국 (건국대학교 의료생명과학 생명과학부) 수상 논문 Clustering Approaches to Identifying Gene Expression Patterns from DNA Microarray Data. (2008). Mol. Cells 25, 279-288. Prof. Dong-Kug Choi's research mainly focuses in the field of Neuroscience investigating the molecular aspects in neurodegeneration and neuroinflammation. Using various molecular, experimental animal and neurogenomics approach, he and his team published a significant number of research articles leading to the discovery of promising candidates in neurodegeneration. For several years, he also systematically analyzed microarray-based class discovery studies for large scale gene expressions. His recent publication investigates the basic principles of clustering of DNA microarray data from crisp clustering algorithms to complex clustering algorithms like fuzzy clustering (M&C 25, 279-278). Based on the theoretical approach, scientific quality, and significant citations, the committee has selected him as the "Best Paper Award Winner", for the year 2011. We congratulate him for his contributions for the betterment of the society and wish him all the best for his future endeavors. |