학회소개 
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이윤태(포항공과대학교)
Dr. Yoontae Lee is a professor in Department of Life Sciences at POSTECH. Dr. Lee obtained his PhD in biological sciences from Seoul National University under supervision of Dr. V. Narry Kim. During his PhD period, he uncovered how microRNAs are generated via identification of key factors in microRNA biogenesis pathway, such as Drosha, DGCR8, RNA polymerase II, and PACT. From 2007 to 2011, he worked as a postdoc in Dr. Huda Y. Zoghbi's lab at Baylor College of Medicine. During this period, he studied on the pathogenesis of spinocerebellar ataxia type-1 neurodegeneration and the role of capicua (CIC)-ATXN1/ATXN1L complex in mouse embryogenesis. In 2011, he joined POSTECH as an assistant professor. His research has been focused on the regulatory role of CIC in lymphocyte development and differentiation and cancer progression. His research group discovered that CIC controls follicular helper T cell differentiation and thymic T cell development to suppress autoimmunity. His research group has also shown that CIC deficiency leads to the expansion of the B-1a cell population at the expense of B-2 cells including follicular and marginal zone B cells. These findings demonstrated that CIC is a key transcription factor in lymphocyte development and differentiation. In addition, his research group has shown that CIC functions as a tumor suppressor in various types of cancer including prostate, breast, liver, and colorectal cancer. Representative papers |