ICKSMCB 2021 / 2021 International Conference of the Korean Society for Molecular and Cellular Biology / November 3 - 5, 2021 / ICC JEJU

Nobel Laureate Lecture

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CRISPR therapy: A miracle cure for tomorrow?



November 4 (Thu), 13:30 -13:55, Tamna Hall

Edward Wong, Ph.D.
GenScript Biotechnology Pte. Ltd, Singapore


Although human diseases can be resulted from several factors, genetic mutations may result in certain human diseases, including cancer, cardiovascular diseases (CVD), diabetes, autoimmune disorder and psychiatric illnesses. Given the rise of interest in immunotherapy, researchers are in the search of a better tool to engineer the T cells for clinical usage. The current available technology, such as the use of viral vector, may cause cytotoxicity and genotoxicity despite the fact of their high efficiency. Not too long ago, CRISPR (clustered regularly interspaced short palindromic repeats) was a cryptic acronym. But, today, CRISPR-Cas9 is emerging as one of the most powerful tool for engineering the genome. Guided by a RNA sequence, the Cas9 endonuclease can be programmed to target the specific sites in the genome. With the understanding of this system, many researchers have started to look into the possibility to edit the genome in order to achieve the therapeutic effect. Or even, to use CRISPR for genome wide screening in order to understand the causal genes for diseases. Empowered by the cutting-edge technology, GenScript Biotech Corporation has become one of the leading life science research and application service and product provider. The company¡¯s mission is to ¡°Make the Human and Nature Healthier through Biotechnology¡±. In this short presentation with case studies, I will take this opportunity to introduce about the capability of GenCRISPR-related services and products.