September 28 (Wed) - 30 (Fri), 2022
Jeju International Convention Center (ICC Jeju)
Satellite Meeting l Tuesday, September 27 - Wednesday, September 28 (2days)
D-Days
Jeju International Convention Center (ICC Jeju)
Satellite Meeting l Tuesday, September 27 - Wednesday, September 28 (2days)
D-Days
¸ÞÀθ޴º
Program
September 28 (Wed), 2022
Sym. 01 Plant Biotechnology to Address Food Security and Climate Change
Plant Biotechnology session will introduce excellent promising results from major crop plants that can be possible solutions for agricultural adaptation to extreme environmental changes due to global climate crisis. In addition, this session will share wonderful results from rice on improvement of nitrogen use efficiency that can help reduce carbon emissions, and also biofortification of functional compounds beneficial for human health.
Organizer & Chair :
Jong-Seong Jeon, Ph.D.(Graduate School of Biotechnology, Kyung Hee University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Motoaki Seki | RIKEN Center for Sustainable Resource Science (CSRS) & Yokohama City University | Japan | Ethanol-mediated survival strategy against drought, heat and high-salinity stresses in plants |
| Ju-Kon Kim | Seoul National University | Korea | The rice NUCLEAR FACTOR-YA5/osa-miR169a module regulates nitrogen use efficiency |
| Sun-Hwa Ha | Kyung Hee University | Korea | Disarming of microProtein PSEUDO-ETIOLATION IN LIGHT family enhances photosynthesis in rice |
| Sichul Lee | National Institute of Agricultural Science | Korea | Improvement of rice yield through the delayed senescence |
| Chaiwat Monmai | Sunchon National University | Korea | Transgenic Rice Seed Containing Protopanaxadiol Reduces Adipogenic Markers During The Differentiation of 3T3-L1 Cells |
Sym. 02 Young Investigators in Women¡¯s Bioscience Forum
This symposium is ¡®KSMCB-Women Bioscience Forum (WBF)¡¯ co-session which introduces new members as early career women investigators working in the diverse fields of molecular and cellular biology. We expect this session would be effective for discussing recent state-of-art research of young women scientists and further implications in biological sciences and treatment of a variety of diseases.
Organizers : Na-Young Song, Ph.D. (Yonsei University, Korea)
Moon Jung Song, Ph.D. (Korea University, Korea)
Moon Jung Song, Ph.D. (Korea University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Haeseung Lee | Pusan National University | Korea | Data-driven drug discovery for cancer therapy by pharmacogenomics approach |
| Jeongeun Hyun | Dankook University | Korea | ESRP2-NF2-YAP Axis in liver diseases |
| Jimi Kim | Gachon University | Korea | Nsp2 Facilitates SARS-CoV-2 Replication by Ensuring Viral Translation in concert with GIGYF2 |
| Song Ih Ahn | Pusan National University | Korea | Human blood-brain barrier-on a chip for studying drug transport mechanisms |
| Somi Kim | Pohang University of Science and Technology (POSTECH) | Korea | p57 Kip2 imposes the reserve stem cell state of gastric chief cells |
Sym. 03 Mitochondrial Responses to Stress and Disease Conditions
Mitochondria are the cell's energy-producing factories, which produce ATP, but at the same time produce reactive oxygen species and are exposed to strong oxidative stress. The mitochondrial response to metabolic or oxidative stress is important for regulating various physiological activities, and when the mitochondrial regulation against stress is disrupted, various diseases occur. In this session, we would like to talk about the signaling mechanisms of various physiological/pathological stresses, related diseases, and treatment targets on the topic of mitochondria, stress, and diseases.
Organizer :
Hyoung Kyu Kim, Ph.D. (Cardiovascular and Metabolic Disease Center, Korea)
Chairs : Hyoung Kyu Kim, Ph.D. (Cardiovascular and Metabolic Disease Center, Korea)
Jong sun Gang, Ph.D. (Sungkyunkwan university, Korea)
Jong sun Gang, Ph.D. (Sungkyunkwan university, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Byoung Heon Kang | Ulsan National Institute of Science and Technology (UNIST) | Korea | Mitochondrial chaperone TRAP1 in human disease progression |
| Kyu-Sang Park | Yonsei University Wonju College of Medicine | Korea | Mitochondrial Calcium in Metabolic Regulation of Adipose Tissues |
| Jeanho Yun | Dong-A University College of Medicine | Korea | Alternative Strategy of neurodegenerative disease treatment: Improvement of mitochondrial dysfunction through mitophagy induction |
| Yohko Yoshida | Juntendo University Graduate School of Medicine | Japan | Brown adispose tissue dysfuntion promotes matabolic disorder in a falling heart |
| Yu Young Jeong | Rutgers, The State University of New Jersey | USA | Broad activation of the parkin pathway induces synaptic mitochondrial deficits tauopathy |
Sym. 04 Genetic Mechanisms of Physiology and Behavior
Various aspects of animal physiology and behavior are regulated by diverse mechanisms involving many genetic factors and neural circuits. The complexity of the mammals sometimes troubles the investigation of the molecular mechanisms and physiological properties of their behaviors. A simple yet powerful animal model, Caenorhabditis elegans, can be used to unravel the mysteries of many biological processes. In this symposium, a variety of animal physiology like sleep, aging, lifespan, and pathogenesis as well as the genetic and neural mechanisms which regulates their properties will be discussed, which provide insights into underlying mechanisms of physiology and behavior in mammals.
Organizers & Chairs : Hyun-Ok Song, Ph.D. (Wonkwang University School of Medicine, Korea)
Kyung Suk Lee, Ph.D. (Kongju National University, Korea)
Kyung Suk Lee, Ph.D. (Kongju National University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Noelle L'etoile | University of California, San Francisco | USA | To sleep perchance to dream |
| Sungjin Kim | Chungnam National University | Korea | Study of Mitochondrial Bioenergetics in Aging using C. elegans |
| Byunghyuk Kim | Dongguk University | Korea | Cell surface protein codes for the formation of sexually dimorphic neural circuits |
| Wooseong Kim | Ewha Womans University | Korea | A Caenorhabditis elegans-based screening platform for antibiotic drug discovery |
| Hoyong Park | Konkuk University | Korea | Sociality regulation by cortico-habenula pathway in an animal model of depression |
Sym. 05 Circadian Rhythms: Clinical Implications and Translational Applications
The research on circadian rhythm has been acknowledged as one of the main themes in biomedical science, as evidenced by Nobel Prize in Physiology or 2017. Decades of works from Nobel Laureates and colleagues in this field have provided the basic understanding of complex molecular and cellular mechanisms driving circadian rhythm. Now we are entering the era in which we can utilize the basic understanding obtained so far to develop clinical applications and improve the quality of life.
This symposium aims to introduce leading-edge researchers emphasizing the bridge between basic science and its application, with the hope to facilitate an extensive exchange of ideas. With that hope in mind, we invited investigators from diverse topics, including neuroscience, molecular and cellular biology, AI-based mathematical biology, and glia biology so that participants with diverse intellectual curiosity can enjoy the symposium altogether.
This symposium aims to introduce leading-edge researchers emphasizing the bridge between basic science and its application, with the hope to facilitate an extensive exchange of ideas. With that hope in mind, we invited investigators from diverse topics, including neuroscience, molecular and cellular biology, AI-based mathematical biology, and glia biology so that participants with diverse intellectual curiosity can enjoy the symposium altogether.
Organizer & Chair : Han Kyoung Choe, Ph.D. (Daegu Gyeongbuk Institute of Science and Technology(DGIST), Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Kyungjin Kim | Daegu Gyeongbuk Institute of Science and Technology(DGIST) | Korea | Circadian regulation of serotoninergic circuit (dorsal raphe nucleus -> orbitofrontal cortex) on modulating depression-like behavior |
| Jae Kyoung Kim | Korea Advanced Institute of Science and Technology (KAIST) | Korea | How modelers can help experimental scientists: Interdisciplinary approach for identifying molecular mechanisms underlying circadian clocks from plants to flies and mammals: |
| Choogon Lee | College od Medicine, Florida State University | USA | An efficient platform for studying human sleep disorders |
| Jin Young Kim | City University of Hong Kong | China | Circadian clock-mediated brain repair system: circadian clocks respond to brain damage to recruit adult neural stem cells for repair |
| Sieun Kim | Korea Advanced Institute of Science and Technology (KAIST) | China | A Ribonuclease that Promotes Longevity by Cleaving Age-dependently Accumulating Circular RNAs |
Sym. 06 The Impact of RNA Control and Regulation on Biological Processes
RNA biology has emerged as one of the most influential areas in modern biology and biomedicine. The discovery of unprecedented classes of RNAs and their functions in biological processes provides profounding roles of various classes of RNA biology both in the biological and clinical sciences. Through this session, world-leading experts in the RNA biology field will share their ongoing research, enabling the audience to learn more about the current status of RNA biology in development and disease.
Organizer & Chair : Jae-Seok Roe, Ph.D. (Yonsei University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Jin-Wu Nam | Hanyang University | Korea | Single-cell analysis of tumor microenvironment-regulating lncRNAs |
| Kwangseog Ahn | Seoul National University | Korea | m6A reader-stabilized viral lncRNAs act as potent regulators of the HCMV life cycle |
| Andrei Goga | University of California, San Francisco | USA | Oncogene Regulated Cellular Communication Alters Tumor Behaviors |
| Sangsu Bae | Seoul National University College of Medicine | Korea | Current Status and Challenges in Genome Editing |
| Jaeil Han | The University of Texas Southwestern Medical Center, Dallas | USA | A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming |
September 29 (Thu), 2022
Sym. 07 Recent Advances in Interorganellar Dynamics and Network
Organelles, membrane-surrounded subcellular compartments of distinct functions, communicate by transferring small molecules, trafficking of vesicles, and direct contacts between membranes. In this session, recent advances in inter-organellar dynamics and trafficking control of ER, Golgi and endosomes will be discussed.
Organizer & Chair : Joo-Yeon Yoo, Ph.D. (Pohang University of Science and Technology (POSTECH), Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Min Goo Lee | Yonsei University College of Medicine | Korea | Unconventional protein secretion of transmembrane proteins |
| Akihiko Nakano | RIKEN Center for Advanced Photonics (RAP) | Japan | Organization of the Golgi Apparatus and Its Neighbors — Insights from the Comparison between Yeast, Plant and Animal Cells — |
| Jihye Seong | Brain Science Institute, Korea Institute of Science and Technology (KIST) | Korea | Live-cell imaging of local protein activity at endosomal vesicles by fluorescent protein-based biosensors |
| Seung-Yeol Park | Pohang University of Science and Technology (POSTECH) | Korea | Vesicular transport is regulated by non-vesicular transport |
| Nari Kim | Pohang University of Science and Technology (POSTECH) | Korea | Spatial interaction profiling of biomolecular condensates on the ER membrane |
Sym. 08 Hepatic Inflammation to Carcinogenesis Transition
Inflammatory conditions are important risk factors for both carcinogenesis and cancer metastasis. However, the underlying causative link between the inflammatory changes in the organ and cancer is unclear. To uncover this issue, we need to bring together a large group of multidisciplinary international experts to investigate inflammation and its relationship to cancer in a variety of patient samples, animal models, and culture systems. These researches will reflect different causes of liver inflammation, such as metabolic dysfunctions, viral infections, a transition of gut-microbiomes, and the effects of immunological intervention in the clinic. We will discuss the changes in different immune cells, gene expression, and the microbiome during the establishment of cancer in animal models and correlate them with patient data, including epigenetic markers.
Organizer & Chair : You Jeong Lee, Ph.D.(Seoul National University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Su Jong Yu | Seoul National University College of Medicine | Korea | Effect of gut microbiota-targeting immune modulation with Multi-Biotics in non-alcoholic fatty liver disease & hepatocarcinogenesis |
| Seung-Oe Lim | Purdue University | USA | Development and Preclinical Evaluation of Immuno-Oncology Drugs |
| Kyun-Hwan Kim | School of Medicine, Sungkyunkwan University | Korea | Inhibition of Non-alcoholic Steatohepatitis by Targeting Paraoxonase 2 |
| Lee, Jung Weon | Seoul National University | Korea | TM4SF5-mediated pro-inflammatory immune environment for hepatic carcinogenesis |
| Tae-You Kim | Seoul National University College of Medicine | Korea | cfDNA epigenetic signature of NASH and HCC |
| Andrei Phillip David | University of the Philippines Diliman | Philippines | The Novel RRAS R78W and E63D Mutants Identified in Young-Onset Colorectal Cancer Induce Cytoskeletal Remodeling and Formation of Invasive Structures |
Sym. 09 The Forefront of Biomedical Research - Gene Therapy and Genome
Editing
Editing
With advancement of biotechnology, convergence of basic research on genetics and biomedical science has provided the basis, for various breakthroughs and follow-up applications of gene therapy & genome editing. This new advancement is becoming increasingly relevant to our lives. This session will look into recent translational research and applications in gene therapy & genome editing in the health problem. In particular, this session will provide a successful example of translational research of gene therapy & genome editing in health problems. From this session, audience can easily follow-up recent innovative researches and applications in the fields of gene therapy & genome editing.
Organizer & Chair : Jeong Hun Kim, M.D. Ph.D.(Seoul National University College of Medicine, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Marcus Fruttiger | UCL Institute of Ophthalmology | UK | Metabolic Changes Associated with Macular Telangiectasia of Retinal Neurodegeneration |
| Jeong Hun Kim | Seoul National University College of Medicine | Korea | Clinical Trials using Genome Editing for IRD in Korea |
| Yeon-Soo Kim | Chungnam National University | Korea | Current Biomedical Applications of Gene Therapy |
| Dong Hyun Jo | Seoul National University College of Medicine | Korea | Genome Editing for Retinal Diseases |
| Esther YG Tak | MGH, Harvard Medical School | USA | Genome-wide Epigenetic Editing of Human Microsatellite Repeats Using Engineered Zinc Finger Transcription Factors |
Sym. 10 Neuroscience of Emotion and Social Homeostasis
Many emotional disorders are associated with impairments in social cognition and subsequent behaviors. Thus, it becomes crucial to preserve proper social interaction and good emotional status. This symposium session aims to understand how emotion and social homeostasis link together from molecular aspects to large-scale neural circuit levels.
Organizer & Chair : Myungjin Kim, Ph.D. (Korea Brain Research Institute, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| MYUNGJIN KIM | Korea Brain Research Institute (KBRI) | Korea | Neuroscience of Emotion and Social Homeostasis: Decoding Molecular Responses to Social Stress |
| Sung Han | Salk Institute for Biological Studies | USA | The neural basis of panic-like behavioral and somatic symptoms and their rescue in mice |
| Sehoon Keum | Institute for Basic Science (IBS) | Korea | Genetic and circuit mechanisms of emotional empathy |
| Choong-Wan Woo | Sungkyunkwan University | Korea | Homeostasis: A key to understanding the brain dynamics and intelligence |
| Eric Y. Choi | University of Maryland School of Medicine | USA | Cell subtype specific role of Nab2 in cocaine seeking behavior |
Sym. 11 Plant Receptor Kinase Signaling
Plants have a large family of membrane-localized receptor kinases (RKs) that sense extracellular signals to control plant growth, development, immunity, and stress response. Functional characterization and identification of the cellular signaling of RKs are essential for understanding how plants communicate with their environments for survival and reproduction. This symposium covers recent advances in plant receptor kinase signaling and technological improvements in studying RK signaling and their biology.
Organizer & Chair : Eunkyoo Oh, Ph.D. (Korea University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Yoshikatsu Matsubayashi | Nagoya University | Japan | Peptide-Receptor kinase signaling mediating nitrogen homeostasis in plants |
| Jungmook Kim | Chonnam National University | Korea | Role of signaling peptides during plant development in response to cold stress |
| Man-Ho Oh | Chungnam National University | Korea | Functional Analysis of Receptor-Like Kinases in Arabidopsis thaliana |
| Eunkyoo Oh | Korea University | Korea | Chemical control of plant immune signaling with an engineered receptor pair |
Sym. 12 Recent Advances in Microbiome for Novel Therapeutics
The ecosystems of higher organisms including human are maintained through mutualistic interaction between host and microbiota. There were dramatically increased interests on human microbiome, and the effects of microbiome on various chronic diseases has been widely accepted. This session will cover basic, applied, and translational research on the functions and underlying mechanism of human microbiome. This session will provide the state-of-art lectures on basic understanding complicated host-microbes interaction and potential application to biomedical sciences.
Organizer & Chair : GwangPyo Ko, Ph.D.(Seoul National University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| GwangPyo Ko | Seoul National University | Korea | Novel microbiome therapeutics against metatolic and immune diseases |
| Sungwhan Oh | Harvard Medical School | USA | Symbiont-derived immunomodulatory lipid mediators: Molecular dissection of host-microbiota-diet interaction |
| Yong-Sun Bahn | Yonsei University | Korea | Genome-Wide Functional Analysis of Brain Infection Mechanisms in Human Fungal Pathogens |
| Heenam Stanley Kim | Korea University | Korea | Current Status and the Future of the Microbiome Therapeutics |
| Myungsuk Kim | Korea Institute of Science and Technology (KAIST) | Korea | Systems Genetic Analysis of Atherosclerosis and Gut Microbiota in a Hyperlipidemic Diversity Outbred F1 Mouse Population |
Sym. 13 Host Immune Evasion and Antibiotic Resistance in Bacterial Pathogen
Antibiotic-resistant bacterial infections and the recent prevalence of outbreaks of viral infections remain a leading cause of infection-associated mortality in the world and pose an enormous threat to public health and the economy. Therefore, there is an urgent need to identify novel therapeutic targets and antimicrobials. To develop therapeutic options that have novel mechanisms of action, host-pathogen interaction has long been studied as one of the important environmental cues to raise antibiotic resistance during infection. This symposium will be dedicated to the recent researches related to host-pathogen interactions, development of antibiotic resistance, and chemotherapeutic options.
Organizer & Chair : Kyeong Kyu Kim, Ph.D. (Sungkyunkwan University, Korea)
Wonsik Lee, Ph.D. (Sungkyunkwan University, Korea)
Wonsik Lee, Ph.D. (Sungkyunkwan University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| David G Russell | Cornell University | USA | What Determines Differential Drug Susceptibility of M. tuberculosis in vivo? |
| Eun-Kyeong Jo | College of Medicine, Chungnam National University | Korea | Autophagy and host-directed therapy for mycobacterial infection |
| Hyungjin Eoh | Keck School of Medicine, University of Southern California | USA | Mining mycobacterial central carbon metabolism: new antibiotic targets against drug resistant tuberculosis |
| Wonsik Lee | Sungkyunkwan University | Korea | Genome Profiling to identify genetic locus for Staphylococcus aureus invasion |
| Kyu-Young Sim | Seoul National University | Korea | Mycoplasma fermentans infection induces human necrotic neuronal cell death via IFITM3-mediated amyloid-beta (1-42) deposition |
Sym. 14 Stem Cell-Based Modeling for Development and Disease
Stem cells are not only the cell source for regenerative medicine but also the model system for understanding the mechanisms of development and diseases. Due to advances in stem cell biology, along with biotechnologies, stem cell-based modeling to recapitulate physiology as well as diseases in human, provide important knowledges. This section will cover the recent advance of stem cell-based modeling and show the future direction in this field of science.
Organizer & Chair : Cha, Hyuk-Jin, Ph,D. (Seoul National University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Cantas Alev | Kyoto University | Japan | Reconstructing human axial development & somitogenesis in vitro |
| Hyuk-Jin Cha | Seoul National University | Korea | Dedifferentiation to fetal-like status by partial reprogramming promotes regeneration |
| Hanseul Yang | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Epigenetic regulation of hair follicle stem cell maintenance and differentiation |
| Kihyun Lee | University of California, San Francisco, USA / Gladstone Institute of Cardiovascular Disease | USA | Dissecting human diseases with genetics and stem cells |
| Gahyang Cho | Korea Institute of Science and Technology (KAIST) | Korea | PRMT1-mediated arginine methylation of Neurogenin 3 is required for pancreatic endocrine development from hESCs |
Sym. 15 Recent Advances in Genetics of Human Diseases
Human genetics aims to understand human diseases, and eventually help people by improving prediction, prevention, and treatment of diseases. Completion of human genome project and introduction of next generation sequencing technology enabled understanding many diseases of varying clinical features. However, complete molecular picture describing the correlation between genetic variants and phenotypes still remains to be improved. And this is perhaps the only way to ensure development of efficient therapeutic interventions. In this session, investigators from genetics fields with various expertise will present their recent works on brain diseases and cancer, covering genetic network, molecular mechanism, physiological pathway, and strategy on treatment.
Organizer & Chair : Murim Choi, Ph.D. (Seoul National University College of Medicine, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Joon-Yong An | Korea University | Korea | Shared gene regulation in autism-associated transcriptional regulators in neurodevelopment |
| Yong-Seok Lee | Seoul National University College of Medicine | Korea | Molecular and Cellular approaches to understand the mechanism of cognitive deficits in Rasopathies |
| Gaia Novarino | Institute of Science and Technology Austria | Austria | Studying cortical development through the lens of human disorders |
| Jinkuk Kim | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Antisense oligonucleotide therapy for genetic diseases in the brain |
| Jungmin Choi | Korea University College of Medicine | Korea | Spatiotemporally resolved single-cell analysis delineates early esophageal squamous carcinogenesis |
Sym. 16 Nutrient Sensing and Signaling for Health and Disease
The main themes of this session are: 1) Explore physiological sensing and signaling control by amino acids and glucose; 2) Examine physiological alterations in nutrient sensing and signaling; 3) Discuss alterations in nutrient sensing and signaling with health and diseases. This session will present the latest research findings and foster engaging discussion on: Amino acid sensing and signaling pathways, Glucose sensing and signaling pathways, Interaction of nutrient sensing pathways, and Nutrient signaling across the life cycle.
Organizer : Jung Min Han, Ph.D. (Yonsei University, Korea)
Chairs : Jung Min Han, Ph.D. (Yonsei University, Korea)
Myunghee Kim, Ph.D. (Korea Research Institute of Bioscience & Biotechnology (KRIBB), Korea)
Myunghee Kim, Ph.D. (Korea Research Institute of Bioscience & Biotechnology (KRIBB), Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Sunghoon Kim | Yonsei University | Korea | Integrated control of amino acid and energy metabolism by aminoacyl-tRNA synthetase |
| Greg Seong-Bae Suh | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Systems nutrient sensing in flies and mice |
| Sheng-Cai Lin | Xiamen University | China | Glucose and metabolites control cell fate |
| Sungwhan Oh | Harvard Medical School | USA | A tale of two molecules: BCAA-derived metabolites regulating metabolism and immunity |
| Sung Shin Ahn | Konkuk university | Korea | FRA1:c-JUN:HDAC1 complex downregulates filaggrin expression upon TNFα and IFNγ stimulation in keratinocytes |
Sym. 17 Biology of Auditory System: Understanding How We Hear
The auditory organ has a complex and sophisticated structure to hear sound, and therefore the formation mechanism is also complex and there are many parts that are still not understood. Recently, the prevalence of hearing loss due to an aging population and changes in the living environment is continuously increasing. This symposium will cover the latest knowledge from the basics of hearing to translational research, such as the development of hearing organs, mechanoelectrical transduction, which is the core of sound sensing, the mechanism and genetics of hearing loss, and treatment for hearing loss.
Organizer : Heon Yung Gee, M.D. Ph.D. (Yonsei University College of Medicine, Korea)
Chairs : Heon Yung Gee, M.D. Ph.D. (Yonsei University College of Medicine, Korea)
Chul Hoon Kim, M.D. Ph.D. (Yonsei University College of Medicine, Korea)
Chul Hoon Kim, M.D. Ph.D. (Yonsei University College of Medicine, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Jinwoong Bok | Yonsei University College of Medicine | Korea | Establishing the hair bundle architecture of auditory hair cells |
| Jung-Bum Shin | University of Virginia | USA | Molecular mechanisms underlying hair cell sensitivity and maintenance |
| Gunsoo Kim | Korea Brain Research Institute | Korea | Integration of sound and movement in the mouse auditory midbrain |
| Seung-Hee Lee | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Flexible representation of auditory information in the mammalian cortex |
| Jong Bin Choi | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Dysregulated ECM remodeling proteins lead to aberrant osteogenesis of Costello syndrome iPSCs |
Sym. 18 Progress, Challenge, and Prospects in Genetic Engineering
Amazing advances have been made in genome engineering technology, resulting in the ability to modify the genome sequence in most all eukaryotic cells. Genome engineering technology has made it possible to expand the scope of the contribution of genetics to human diseases by facilitating the generation of more accurate cells and animal models of human diseases. In addition, it has laid the foundation to develop new therapeutic tools for human disease, and it is expected that practical therapeutics will come out soon. This session includes the overall contents from the basics to the application of genome engineering using CRISPR, and the future value will be considered.
Organizer & Chair : Ho Lee, Ph.D. (National Cancer Center, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Yong-Sam Kim | Korea Research Institute of Bioscience and Biotechnology(KRIBB) / GenKOre | Korea | Self-sufficient minimalism in CRISPR technoloyg: TaRGET |
| Hui Yang | Chinese Academy of Sciences | China | High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects |
| Kyoungmi Kim | Korea University College of Medicine | Korea | Targeted mutagenesis in mouse cells and embryos using an enhanced prime editor |
| Dongho Choi | Hanyang University School of Medicine | Korea | Gene editing with chemical derived hepatic progenitors for the treatment of chronic liver diseases |
| Hyun-Jun Choi | Soonchunhyang University | Korea | The role of GSK3β on Protein Quality Control in the ALS Pathogenesis |
September 30 (Fri), 2022
Sym. 19 Combating Emerging and Chronic Viruses: Understanding Host-Virus
Interactions and Pathogenesis
Interactions and Pathogenesis
The COVID19 pandemic which was declared as one of public health emergency of international concern (PHEIC) by WHO has brought us many formidable challenges in all aspects of our lives but also advanced science of mRNA vaccines. Understanding of host virus interactions and pathogenesis would be a key process to develop anti-virals and vaccines and to combat both emerging and chronic diseases. In this session, we invite 5 speakers who will discuss the pathogenesis and host-virus interactions of SARS-CoV2, MERS-CoV, Severe Fever with Thrombocytopenia Syndrome (SFTS) Virus and Herpes Viruses to provide insights on opportunities to develop effective viral therapeutics and vaccines. The session will also address the critical importance of one health approach at the human-animal-ecosystem for combating emerging viruses. To accomplish 100 days mission to respond to future pandemics proposed by G7 countries, research preparedness to enlighten the interactions of major known viruses with hosts would be a pre-requisite.
Organizer & Chair : Youngmee Jee, M.D., Ph.D. (Institut Pasteur Korea, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Nam-Hyuk Cho | Seoul National University College of Medicine | Korea | Pathogenic inflammatory network in COVID-19 |
| Malik Peiris | University of Hong Kong | China | Threats from emerging coronaviruses |
| Moon Jung Song | Korea University | Korea | Viral Modulation of NAD+-dependent signaling molecules |
| Euiho Kim | Institut Pasteur Korea | Korea | Exploring underlying mechanism of vaccine-induced immunity |
| LEE, KEUN HWA | Hanyang University College of Medicine | Korea | Severe Fever With Thrombocytopenia Syndrome Virus Infection: From Epidemiology to Immunopathogenesis |
Sym. 20 Ferroptosis: An Emerging Form of Regulated Cell Death in Human
Diseases
Diseases
Ferroptosis is a recently recognized cell death modality induced by lipid peroxidation and is distinguished from other form of cell death. Increasing evidence suggest that ferroptosis is implicated in various human diseases such as cancer, neuronal and cardiovascular diseases. We believe that increased understanding of ferroptosis pathways may promote the development of better drugs for ferroptosis-related diseases.
Organizer & Chair : Eun-Woo Lee, Ph.D. (Korea Research Institute of Bioscience & Biotechnology (KRIBB), Korea)
Cheol-Sang Hwang, Ph.D. (Pohang University of Science and Technology (POSTECH), Korea)
Cheol-Sang Hwang, Ph.D. (Pohang University of Science and Technology (POSTECH), Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Marcus Conrad | Helmholtz Zentrum München | Germany | Ferroptosis: From basic mechanisms to therapeutic opportunities |
| Cheol-Sang Hwang | Pohang University of Science and Technology (POSTECH) | Korea | Regulation of Ferroptosis by the Ac/N-Degron Pathway |
| Jong-Lyel Roh | CHA Bundang Medical Center, CHA University | Korea | A novel anti-cancer therapy for overcoming cancer therapeutic resistance by targeting iron metabolism and induction of ferroptosis |
| Dongryeol Ryu | Sungkyunkwan University School of Medicine | Korea | L-threonine mediated DAF-16/HSF-1 activation inhibits ferroptosis and increases healthspan |
| Gahee Song | Kyung Hee University | Korea | Vanillic acid improves muscle atrophy by regulating sirtuin 3-mediated mitochondrial dynamics in colon cancer-induced cachexia |
Sym. 21 Recent Revolutionary Updates on the Experimental and Computational
Methods for the Protein Structure
Methods for the Protein Structure
X-ray crystallography dominated the Structural biology field until just five years ago. However, the advances and the invention of cryo-electronmicroscopy and single-molecule analysis have destroyed its domination. Furthermore, the AI-based structure prediction programs provide almost equivalent structural information primarily at the static states. This series of rapid changes in the scientific environments forced structural biology to adapt to the changing situations. The evolution of structural biology is required to survive in this rapidly-changing scientific environment.
This session consists of four outstanding scientists representing four subfields in exploring the protein molecules at the molecular levels: X-ray crystallography, cryo-electronmicroscopy, single-molecule analysis, and computational biology fields. Shortly, the subfields should adapt to the changing scientific environments by working together intimately or by multiple expertise. These talks will provide the directions of the evolution of structural biology.
This session consists of four outstanding scientists representing four subfields in exploring the protein molecules at the molecular levels: X-ray crystallography, cryo-electronmicroscopy, single-molecule analysis, and computational biology fields. Shortly, the subfields should adapt to the changing scientific environments by working together intimately or by multiple expertise. These talks will provide the directions of the evolution of structural biology.
Organizers : Nam-Chul Ha, Ph.D. (Seoul National University, Korea)
Ho-Min Kim, Ph.D. (Korea Advanced Institute of Science and Technology (KAIST) & Institute for Basic Science(IBS), Korea)
Ho-Min Kim, Ph.D. (Korea Advanced Institute of Science and Technology (KAIST) & Institute for Basic Science(IBS), Korea)
Chair : Nam-Chul Ha, Ph.D. (Seoul National University, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Tae-Young Yoon | Seoul National University | Korea | Watching helical membrane proteins fold |
| Ji-Joon Song | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Integrative structural study on Huntington’s disease protein to reveal Huntingtin as a modular scaffolding machine |
| Astushi Nakagawa | Osaka University | Japan | Structural Studies of the Multi-drug Efflux Pump, MexAB-OprM, from Pseudomonas aeruginosa |
| Chaok Seok | Seoul National University | Korea | Searching Chemical Space and Protein Space in the Era of Accurate Protein Structure Prediction |
| Mark Borris Aldonza | Seoul National University | Korea | Pan-cancer widespread multi-targeted therapy resistance via drug-induced secretome fucosylation |
Sym. 22 Epigenetic Regulation of Gene Expression
Epigenetic regulation mediated by histone modifications, DNA methylation, and non-coding RNAs, among others, play pivotal roles in gene expression. Research over the last two decades has uncovered the role of epigenetic regulators in various human disorders and fatal diseases. This session comprises five speakers who actively study the epigenetic regulation of gene expression.
Organizer & Chair : Jaehoon Kim, Ph.D.(Korea Advanced Institute of Science and Technology, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Sungchul Hohng | Seoul National Univerisity | Korea | RNA polymerase is a damage sensor that makes R-loops at DNA damage sites |
| Yali Dou | University of Southern California | USA | Insights for canonical and non-canonical functions of histone methyltransferase MLL in Cancer |
| Minhee Park | Korea Advanced Institute of Science and Technology (KAIST) | Korea | To build and visualize chromatin: Understanding epigenetic memory |
| Kim, Jeong-Hoon | Korea Research Institute of Bioscience and Biotechnology (KRIBB) | Korea | Hypoxia stabilizes SETDB1 to maintain genome stability |
| Keun Hong Son | Seoul National University | korea | Integrative mapping of the dog epigenome: reference annotation for comparative inter-tissue and cross-species studies |
Sym. 23 Muscle Biology Beyond Aging, Sarcopenia, and Frailty
This session will share the most recent research trends on muscle aging and related diseases (e.g., sarcopenia, frailty, and cellular senescence), which are essential for promoting healthy aging in the elderly population. The nominated speakers will lecture on a wide range of subjects, from the fundamentals to translational research.
Organizer :
Seong-Kyu Choe, Ph.D. (Wonkwang University, Korea)
Chairs : Seong-Kyu Choe, Ph.D. (Wonkwang University, Korea)
Jong-Sun Kang, Ph.D.(Sungkyunkwan university, Korea)
Jong-Sun Kang, Ph.D.(Sungkyunkwan university, Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Jong-Sun Kang | Sungkyunkwan university School of Medicine | Korea | The role of Prmt1 in neuromuscular function |
| Young C. Jang | Emory School of Medicine & Georgia Tech | USA | Integrative bioengineering approaches to rejuvenate aging skeletal muscle |
| Johan Auwerx | Ecole Polytechnique Fédérale Lausanne (EPFL) | Switzerland | Ceramide de novo Synthesis Links Muscle Disorders With Mitochondrial And Protein Homeostasis |
| Yong Ryoul Yang | Korea Research Institute of Bioscience and Biotechnology(KRIBB) | Korea | The rejuvenation of aged muscle by CLCF1 |
| Ju-Chan Park | Seoul National University | Korea | Multiple isogenic GNE-myopathy disease modeling with mutation specific phenotypes from human pluripotent stem cells by base editors |
Sym. 24 Immunological Research in the Era of Single Cell Biology
Single cell technologies are revolutionizing our fundamental understanding of immunology. Especially, single cell analysis enables dissection of immune cell heterogeneity, identification of novel immune cell types, measurement of continuum of immune cell states, and analysis of clonal expansion of immune cells. In this symposium, five speakers will discuss how to apply cutting-edge single cell technologies for immunological research in different physiological conditions or diseases.
Organizer & Chair : Jihwan Park, Ph.D. (Gwangju Institute of Science and Technology (GIST), Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Je-Min Choi | Hanyang University | Korea | Single-cell transcriptomic analysis identifies heterogenous steady-state CD4+ T cells in mice with unique effector functions |
| Jongsoon Lee | Soonchunhyang University | Korea | Regulation of Adipose Tissue NK Cells in Obesity and Its Implication in the Development of Type 2 Diabetes |
| Eui-Cheol Shin | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Identification and characterization of unconventional T cells by single cell biology |
| Joo-Hyeon Lee | University of Cambridge | UK | Dynamics of stem cell fate directed by immune cells in the lung |
| Eun Seo Park | Daegu Gyeongbuk Institute of Science and Technology(DGIST) | Korea | Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics |
Sym. YI
Organizer & Chair : Ji Min Lee, Ph.D. (Korea Advanced Institute of Science and Technology (KAIST), Korea)
| Name(Eng) | Organization | Nationality | Title |
|---|---|---|---|
| Woo Yong Park | Kyung Hee University | Korea | Ellagic Acid Improves Benign Prostate Hyperplasia by Regulating Androgen Signaling and STAT3 |
| Nagarajan Vinod | Korea Institute of Radiological & Medical Sciences | Korea | Combination of 131I-rituximab and Genipin Induced Cytotoxicity in Human Raji Cells |
| Jeongsik Kim | Korea Advanced Institute of Science and Technology (KAIST) | Korea | Actin disruption induces large vacuole formation in matrix-detached mammary epithelial cells |
| Sang-Ho Yoon | Hanyang University | Korea | Landscape of Cell Type-Specific Non-Coding Transcriptomes in Tumor Microenvironment |
| Young Rae Ji | Korean Brain Research Institute (KBRI) | Korea | Function of Bidirectional Sensitivity in the Otolith Organs Established by Transcription Factor Emx2 |
| Hwa Jin Kim | Sungkyunkwan University | Korea | DBC1 is a key positive regulator of enhancer epigenomic writers KMT2D and p300 |
| Yong Geun Jeon | Seoul National University | Korea | Ubiquitin Ligase RNF20 Controls Sequential Thermogenic Activation of Brown and Beige Fat |
