September 28 (Wed) - 30 (Fri), 2022
Jeju International Convention Center (ICC Jeju)

Satellite Meeting l Tuesday, September 27 - Wednesday, September 28 (2days)

D-Days

HnS Bio

September 29(Thu), 12:40-13:30(50min.), 5F Tamna Hall A

NanoTemper Technologies has developed a novel approach to the characterization of molecular interactions: Spectral Shift. This new technology is the driving engine for our latest product releases Dianthus and Monolith X. Both instruments feature a combination of the new isothermal spectral shift detection with the established MST/TRIC technology. The instruments enable characterization of in solution interactions for a wide range of biomolecules, even for challenging samples such as PROTACs, membrane proteins, intrinsically disordered proteins, and cell lysates. The instruments enable mass-independent, in-solution measurements with lowest sample consumption and even in the presence of aggregation. Dianthus and Monolith X can not only be used to validate your results from other biophysical methods but also to characterize your most challenging interactions. Don’t miss out on the opportunity to learn about this game-changing new biophysical assay technique.

possibilities for protein research - Several case studies on QC and in-depth characterization of biologics, gene therapy vectors and more.
NanoTemper Technologies has developed the Prometheus which the scientific community has chosen because it consistently delivers high-resolution data that reveals details in proteins and formulations that are missed by other technologies.
The latest model (Prometheus Panta) is equipped with the current gold standard for protein stability characterization (label free nanoDSF + backreflection), and a novel type of DLS/SLS enabling new experimental possibilities.
Besides standard applications, the new type of DLS/SLS now allows dynamic light scattering (DLS) experiments in tandem with static light scattering (SLS), label free nano-differential scanning fluorimetry (nanoDSF) and backreflection, along an entire thermal ramp, to gain information on conformation, thermal stability, turbidity, radius, size distribution and more, on your protein of interest or formulation.
In this presentation the measurement principles of Prometheus Panta and several case studies will be shown that demonstrate how i.e. Merck Healthcare KGaA, Novartis, Boehringer Ingelheim and others use the standard and new possibilities of Panta for in-depth characterization and QC of biologics, gene therapy vectors and more.