ICKSMCB 2022 / 2022 International Conference of the Korean Society for Molecular and Cellular Biology / September 28 - 30, 2022 / ICC JEJU

Nobel Laureate Lecture

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Geninus



September 30(Fri), 12:40-13:30(50min.), 3F Halla Hall

Donghyun Park

Technical applications of single-cell analysis

Donghyun Park, Ph.D.
Director of Research center, Geninus Inc.

Single-cell RNA sequencing (scRNA-seq) allows us to profile transcriptome of each individual cells that constitute various subpopulations, which offers important insight on both normal physiology and pathological condition. Various RNA-seq methods have been developed to open new possibilities of profile gene expression in unprecedent dimensions. Sample preparation, integration of multi-omics data, and cost effectiveness have been greatly improved. In addition, Visium (10X Genomics) platform became recently available for researchers to offer spatial transcriptomics analysis that localize transcripts by capturing mRNA with spatial barcoding. In this lecture, recent advances in single cell RNA-seq analysis are introduced and their applications are discussed.