ICKSMCB 2023 / 2023 International Conference of the Korean Society for Molecular and Cellular Biology / September 28 - 30, 2023 / ICC JEJU

Nobel Laureate Lecture

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November 7Tue, 12:30-13:20(50min.), 1F Yeongju Hall

Yongtae, Kim

Peptide nucleic acids: characteristics, applications, and potential

Yongtae, Kim, Ph.D.
Seasun biomaterials

Peptide nucleic acids (PNAs) are a class of synthetic nucleic acid analogs that have gained significant attention in the field of molecular biology due to their unique properties. PNAs have several features that make them attractive as research tools, including high binding affinity to complementary DNA and RNA sequences, resistance to enzymatic degradation, and a structure that is amenable to chemical modification. Recently, we have developed a novel dual-functional PNA probe optimized for digital PCR technologies. This new PNA probe exhibited superior specificity and sensitivity compared to TaqMan(LNA) probes, addressing the challenges previously faced when using traditional PNAs as probes in digital PCR. The innovation of this probe for enhancing the accuracy and reliability of digital PCR holds significant promise in the fields of molecular diagnostics and life sciences. In this session, we will discuss the characteristics of PNA and explore its diverse applications in biotechnology, including molecular diagnostics and therapeutics.