¼ÛÇö±Ô (°í·Á´ëÇб³ »ý¸í°úÇкÎ) Hyun Kyu Song is a Professor at Division of Life Sciences, Korea University. He received his PhD degree from Seoul National University in 1997 and trained as a postdoctoral researcher at Max-Planck Institute for Biochemistry and also at Harvard Medical School. He has been recognized as a leading structural biologist in the field of protein degradation. He uses X-ray crystallography in combination with various biochemical and biophysical techniques to study the molecular recognitions and cellular functions of protein breakdown system in the cell. His group determined a number of structures of prokaryotic proteasome homologs including HslV/HslU and ClpX/ClpP from diverse species, as well as eukaryotic ubiquitylating enzymes such as E1-activating, E2-conjugating enzymes and E3-ligases. Most recently, Prof. Song and his colleagues focus on autophagic enzymes which share mechanical similarity with ubiquitylating enzymes. Prof. Song has been recognized as Top 10 Bionews 2010 in Korea with his elucidation of ClpP activation mechanism and a potential application for antibiotics development. In addition, this achievement was chosen as Outstanding Research Output by Korea's National Science & Technology Commission in 2011. He received award for Outstanding Research Output in 2011 from Korea's Ministry of Education, Science and Technology with his contribution to the determination of UBR box from Ubr1 ubiquitin E3-ligase. He also received award for Outstanding Research Output in 2012 from Korea's Ministry for Health, Welfare & Family Affairs with his work on the activation mechanism of autophagic E1-enzyme Atg7. Representative papers |
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