학회소개 
| 한국분자·세포생물학회 학술상 생명과학상 수상자 | |
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안지훈 (고려대학교 생명과학대학 생명과학과) Professor Ahn has made fundamental contributions to the understanding of the control of flowering time by ambient temperature changes. Best known of Ahn's discoveries is that a small group of genes that act within a distinct pathway, the ambient temperature pathway, mediate ambient temperature response. This finding was one of the first clues to the molecular genetic mechanism of plants' behavior to the ambient temperature changes. There is increasing concern about the potential impact of global temperature changes, which significantly affect ambient temperature, on plant development. Although a great deal of progress has been made in our understanding of the regulation of plant development by low temperature, less is currently known about the molecular mechanisms underlying the responses of plants to changes in ambient temperature. His findings have provided a new explanation for the genetic mechanisms by which plants respond to ambient temperature changes. He proposed the ambient temperature pathway genes control flowering time (Nature Genetics). He has shown that SHORT VEGETATIVE PHASE (SVP) acts within the thermosensory pathway and plays a role in ambient temperature response via direct binding to the cis-acting element of FLOWERING LOCUS T (FT), an important floral integrator gene (Genes and Development). In addition, he has shown that small RNAs play an important regulatory role in ambient temperature signaling and that SVP provides a link between the thermosensory pathway and ambient temperature responsive miRNAs (Nucleic Acids Research). He has recently showed that SHORT VEGETATIVE PHASE (SVP) and FLOWERING LOCUS M-beta (FLM-beta), two MADS-box proteins, form a complex that mediate temperature response in plants (Science). He also showed that control of the abundance of SVP-FLM-beta repressor complex at the transcriptional level (FLM) and at the posttranslational level (SVP) is important for plants' response under continuingly changing ambient temperature conditions. Representative papers |
| 한국분자·세포생물학회 학술상 Molecules and Cells (M&C) 우수논문상 수상자 | |
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백광희 (경희대학교 생명과학대학 유전공학과) 수상 논문 Regulation of Vascular Endothelial Growth Factor Signaling by miR-200b. (2010). Mol. Cells 32, 77-82. Angiogenesis is a formation of new blood vessels from preexisting vasculature in physiological and pathological conditions. When tumors are formed, angiogenesis plays a crucial role in the tumor growth, invasion, and metastasis. In tumor angiogenesis, one of the most important regulators |