Çѱ¹ºÐÀÚ·¼¼Æ÷»ý¹°ÇÐȸ Çмú»ó »ý¸í°úÇлó ¼ö»óÀÚ | |
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Professor Ildoo Hwang received his B.S. and M.S. degrees at Seoul National University and a Ph.D. degree in Plant Biology from the University of Maryland at College Park. After his breakthrough research to lay out the cytokinin signaling cascade during postdoctoral training at Harvard Medical School, he joined the Department of Life Sciences at Pohang University of Science and Technology as a professor in 2003. Since then he has carved out a niche, undoubtedly leading the plant signaling research field where his group has been involved in exploring diverse aspects of the signal transmission and networks underlying plant growth and development to achieve sustainable crop production. His research focuses on comprehending how plants integrate developmental and environmental cues and respond to their ambiance, to optimize plant growth and productivity. Recently, his research group discovered JULGI (ÁÙ±â) proteins involved in the development of phloem and became the world’s first to identify ways to promote the transporting capacity of plants and increase plant productivity. His researches have featured in Nature Plants, Nature Communications, Nature Cell Biology, Developmental Cell, Plant Cell, Molecular Plant, PNAS, Nature and Science to name a few. He is a Seok-Cheon distinguished professor in POSTECH and honored with the best research award from the Korean Society of Plant Biologists, the best research award from the Korean Ministry of Agriculture, Food and Rural Affairs, Macrogen scientist award from the Korean Society for Molecular and Cellar Biology, Cargill life science award from the Korean Academy of Science and Technology, and Postechian research award from POSTECH. Representative papers |
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Çѱ¹ºÐÀÚ·¼¼Æ÷»ý¹°ÇÐȸ Çмú»ó Molecules and Cells (M&C) ¿ì¼ö³í¹®»ó ¼ö»óÀÚ | |
±è±¤Ç¥(°æÈñ´ëÇб³), Ȳ¼øÀÏ(University of Illinois at Chicago)
Altered Proteome of Extracellular Vesicles Derived from Bladder Cancer Patients Urine. Mol Cells. 41(3):179-187 (2018) As extracellular vesicles (EVs) are representative of their parental tissues, this has led to the emergence of EVs as a focus in cancer research. Proteomic analysis of EV from biological fluid is a powerful approach to discover biomarkers for human diseases including cancers. While urine represents an excellent source of biomarkers for urologic cancers, there is a high degree of intra-and inter-individual variability in urine specimens. In this study, we investigated the applicability of urine EV by optimization for proteomic profiling and identification of bladder cancer biomarkers. The enrichment of urinary EV demonstrated its capability and applicability of providing a focused identification of biologically relevant proteins in urological diseases. Overall, comparative proteomic analyses of urinary EV from control subjects and bladder cancer patients identified more than 1,200 proteins and provided 56 proteins significantly increased in bladder cancer urine. |